Inclusion criteria:
- All patients with newly diagnosed PDAC
- Minimum ≥18 years old
- During pre-defined time period (by study supervisor) for each certified pancreas center, that regularly implements MDTBs
Exclusion criteria:
- Any other diagnosis than PDAC
- Recurrence of a PDAC
Research method
Prospective study: we aim to include all consecutive patients meeting the inclusion criteria; no sample size calculation is carried out. There is no intervention, and all treatment decisions are descriptively recorded as per the MDTB.
Patients fulfilling the inclusion criteria will be identified in each MDTB over three months. The data used for this study is routinely recorded before and during treatment and prospectively added to the electronic data management system. Data covering individual patients medical history will cover 9 months from first MDTB.
Information collected for this project will cover up the following four key points:
1.) Number and distribution of patients according to the NCCN-criteria (or the equivalent scoring system used by the center)
2.) Treatment approach of each group, differences in ways of treatment among the different
centers
3.) Individual follow-up of each patient. Relative proportion of patients receiving a
potentially curative treatment (i.e. surgery) after nine months, changes in NCCN-subgroups (or the equivalent scoring system used by the center) due to good respond to chemotherapy.
4.) Parameters and outcome of treatment (choice of and changes in chemotherapy, side
effects of treatment, R-status etc.)
Outcomes
Outcome measures include primarily subgroup analyses (i.e. relative proportion, composition of subgroups, exact characteristics of each covering basic information like demographic parameters and disease related parameters) and management of each group in each center including chemotherapy protocols, imaging protocols and surgical approach.